Common Name(s): White mulberry,oxyresveratrol,dual tyrosinase inhibitor

CAS Number: 84929-37-3

DESCRIPTION

What It Does: Provides dual-mechanism oxyresveratrol tyrosinase inhibition brightening from white mulberry.

Why It's Used: Most potent natural dual-mechanism brightener — oxyresveratrol provides competitive and non-competitive tyrosinase inhibition simultaneously, addressing two enzyme binding sites for more complete melanogenesis inhibition than single-mechanism brighteners.

How It Works: Oxyresveratrol (3,3',4,5'-tetrahydroxystilbene): competitive + non-competitive dual tyrosinase inhibition. mulberroside f: additional brightening. resveratrol backbone: sirt1 activity. traditional east asian: silk production mulberry tree heritage.

Typically Found In: Premium brightening,hyperpigmentation treatment

TECHNICAL DETAILS

Primary Category: Active ingredient – brightening / tyrosinase inhibitor

Secondary Functions: Melanin inhibition,hyperpigmentation reduction

Application Areas:

Typical Concentration Range: 0.1%–3%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Synthetic or plant-derived.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. use with spf for maximum efficacy. ewg score: 1.

Works Well With: Niacinamide,vitamin c,alpha-arbutin,tranexamic acid,spf

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Oxyresveratrol dual tyrosinase inhibition provides multiplicative inhibition: competitive inhibition blocks substrate binding; non-competitive inhibition blocks allosteric enzyme activation. two independent enzyme sites addressed simultaneously provides multiplicative rather than additive inhibition — disproportionately potent brightening per molecule.

Last Verified: 2026-03-12

Primary Sources: Cosing database,white mulberry oxyresveratrol review