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Common Name(s): Mortierella glycerides,mortierella glycerides,zygomycete fungal oil,high-gla triglyceride

CAS Number: N/a

DESCRIPTION

What It Does: Provides high-concentration gla as an omega-6 pufa precursor to dgla and anti-inflammatory prostaglandin e1 (pge1) series, with the fungal triglyceride backbone providing sc barrier emolliency.

Why It's Used: Mortierella glycerides are selected for their exceptionally high gla content from fungal fermentation โ€” the mortierella alpina production route delivers 2โ€“3ร— the gla concentration of plant-based sources, providing pharmaceutical-grade anti-inflammatory pro-resolving lipid mediator precursors in a sustainable fermentation format.

How It Works: Gla (c18:3, n-6): ฮด6-desaturase pathway โ†’ dgla โ†’ pge1 (anti-inflammatory) + 15-hetre; pro-resolving lipid mediator synthesis โ†’ reduced leukotriene-mediated inflammation โ†’ ceramide biosynthesis support.

Typically Found In: Anti-inflammatory,eczema,barrier repair

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.5%โ€“20%

SOURCING & ETHICS

Vegan Status: Conditional - feedstock declaration required

Halal Status: Unverified - feedstock declaration required (plant, animal and petrochemical routes all exist)

Source Notes: Plant-derived extract or synthetic. [audit 2026-07-29 rev2: origin-dependent: the same inci exists in plant, animal and petrochemical versions and the name does not discriminate. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Mortierella gla content is consistent across fermentation batches โ€” unlike plant-sourced gla oils where efa content varies with climate and harvest conditions.

Last Verified: 2026-03-22

Primary Sources: Cosing database,mortierella glycerides zygomycete fungal gla review