Back to Ingredient Dictionary

METHOTREXOYL OLIGOPEPTIDE-59

Description

Methotrexoyl Oligopeptide-59 is an innovative synthetic peptide designed for advanced skincare applications. This compound combines the structural elements of methotrexate, a folate antagonist, with a short chain of amino acids to create a unique molecule with potential anti-aging properties.

The peptide works by mimicking the action of methotrexate, inhibiting the enzyme dihydrofolate reductase, which is involved in DNA synthesis and cell proliferation. In skincare, this mechanism is thought to help regulate skin cell turnover and potentially reduce the appearance of fine lines and wrinkles.

Methotrexoyl Oligopeptide-59 is typically used in low concentrations in serums and creams targeting signs of aging. It may enhance skin firmness and elasticity by modulating collagen production and breakdown. The peptide's small size allows for better penetration into the skin compared to larger molecules.

While research on this specific peptide is ongoing, preliminary studies suggest it may offer benefits in improving skin texture and reducing the appearance of photodamage. As with any active ingredient, patch testing is recommended before full application, and it should be used as part of a comprehensive skincare regimen.