Back to Ingredient Dictionary

LYSOPHOSPHATIDYLGLYCEROL

Description

Lysophosphatidylglycerol (LPG) is a bioactive lysophospholipid that plays a crucial role in cellular membranes and signaling processes. This naturally occurring compound is derived from phosphatidylglycerol through the action of phospholipase enzymes. LPG's unique structure consists of a glycerol backbone, a single fatty acid chain, and a phosphate group linked to another glycerol molecule.

In skincare formulations, LPG exhibits multiple beneficial properties. It acts as an effective moisturizer by enhancing the skin's barrier function and reducing transepidermal water loss. LPG also demonstrates anti-inflammatory effects, potentially alleviating symptoms associated with various skin conditions. Research suggests that LPG may modulate immune responses in the skin, making it a promising ingredient for sensitive or reactive skin types.

LPG's amphiphilic nature allows it to function as an emulsifier in cosmetic products, helping to stabilize oil-in-water formulations. Additionally, it may enhance the penetration of other active ingredients, improving overall product efficacy. While further studies are needed to fully elucidate its mechanisms of action, LPG shows promise as a multifunctional ingredient in advanced skincare formulations, particularly those targeting barrier repair, hydration, and inflammation reduction.