Common Name(s): Lactobacillus ferment filtrate,lab ferment
CAS Number: N/a
DESCRIPTION
What It Does: Provides lactobacillus postbiotic metabolites for microbiome-supportive barrier strengthening and anti-acne activity.
Why It's Used: Complete lactobacillus postbiotic providing bacteriocins for anti-s. aureus activity alongside lactic acid exfoliation and exopolysaccharide barrier support in a single ferment ingredient.
How It Works: Bacteriocins (nisin-type) provide selective s. aureus antimicrobial activity supporting healthy microbiome. lactic acid provides mild aha exfoliation and ph acidification. exopolysaccharides provide barrier-supportive film. tlr2 postbiotic activation from cell wall fragments.
Typically Found In: Microbiome skincare,anti-acne products,barrier repair
TECHNICAL DETAILS
Primary Category: Active ingredient – probiotic ferment postbiotic
Secondary Functions: Microbiome balance,prebiotic effect
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5%–10%
SOURCING & ETHICS
Vegan Status: Yes – bacterial fermentation
Halal Status: Yes
Source Notes: Fermentation-derived or plant-extracted.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; beneficial for sensitive skin.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,niacinamide,soothing actives
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Lactobacillus ferment's bacteriocin activity provides selective antimicrobial pressure against pathogenic s. aureus and s. pyogenes while sparing beneficial commensal bacteria — fundamentally different from broad-spectrum antimicrobials that reduce total skin bacterial count including beneficial commensals. this selective pressure supports microbiome diversity and composition rather than simply sterilising the skin surface.
Last Verified: 2026-03-12
Primary Sources: Cosing database,marinelli et al. lactobacillus skin postbiotic review