Common Name(s): Lactobacillus extract filtrate,lactobacillus extract filtrate,lactobacillus lab postbiotic,acid mantle support active
CAS Number: N/a
DESCRIPTION
What It Does: Reinforces skin acid mantle through lactic acid production, provides selective antimicrobial protection from class iia bacteriocins against acne-associated pathogens, and delivers anti-inflammatory trained immunity from tlr2-active cell wall lta.
Why It's Used: Lactobacillus ferments are the most clinically validated postbiotic ingredient class — acid mantle reinforcement, bacteriocin antimicrobial selectivity, and tlr2 immunomodulation are independently documented in clinical dermatology literature.
How It Works: Lab fermentation: lactic acid production (ph 4.5–5.0 acid mantle reinforcement); class iia bacteriocins (membrane pore formation in gram-positive pathogens — selective c. acnes/s. aureus inhibition preserving commensal diversity); lta cell wall fragments (tlr2/tlr6 → il-10 anti-inflammatory tolerance); beta-glucosidase (polyphenol glycoside → aglycone biotransformation, 10–50× sc penetration improvement).
Typically Found In: Microbiome skin care,anti-acne,postbiotic anti-aging
TECHNICAL DETAILS
Primary Category: Active ingredient – skin microbiome support
Secondary Functions: Microbiome balance,prebiotic effect
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.5%–15%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Fermentation-derived or plant-extracted.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; beneficial for sensitive skin.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,niacinamide,soothing actives
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Substrate specificity determines the dominant supplementary bioactive: ganoderma substrate → triterpene aglycones; pomegranate → ellagitannin/urolithin precursors; collagen → bioactive collagen peptides; sea algae → fucoidan derivatives — substrate selection customises postbiotic output beyond the core lab metabolite profile.
Last Verified: 2026-03-22
Primary Sources: Cosing database,lactobacillus postbiotic lab acid mantle microbiome review