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Hydroxyethylpiperazine Ethane Sulfonic Acid

Description

Hydroxyethylpiperazine Ethane Sulfonic Acid (HEPES) is a zwitterionic organic chemical buffering agent widely used in cell culture and biochemical research. In skincare formulations, HEPES serves as a pH adjuster and stabilizer, helping to maintain optimal acidity levels in various products. This ingredient is particularly valuable for its ability to maintain a stable pH between 6.8 and 8.2, which closely mimics the skin's natural pH range.

HEPES offers several benefits in skincare applications. It helps preserve the efficacy of other active ingredients by preventing pH fluctuations that could compromise their stability. The compound also exhibits good biocompatibility and low cytotoxicity, making it suitable for use in sensitive skin formulations. HEPES can enhance the penetration of certain active ingredients, potentially improving their effectiveness.

In cosmetic products, HEPES is typically used at concentrations between 0.1% and 2%. It is compatible with a wide range of skincare ingredients and can be incorporated into various product types, including serums, creams, and gels. While HEPES is generally considered safe for topical use, some individuals may experience mild irritation. As with any skincare ingredient, patch testing is recommended before widespread application.