Common Name(s): Hydrolyzed agrimonia pilosa leaf extract,hydrolyzed agrimonia pilosa leaf extract,botanical/plant hydrolysate,enhanced bioavailability active
CAS Number: N/a
DESCRIPTION
What It Does: Provides the botanical's active phytochemicals in low-mw, water-soluble hydrolysate form with improved sc penetration versus intact source material.
Why It's Used: Hydrolysis of botanical polymers and glycosides improves active delivery — macromolecule digestion generates fragments with improved solubility and penetration for botanical actives that are otherwise too large or insoluble for effective skin delivery.
How It Works: Hydrolysis releases: glycoside-bound polyphenols → free aglycones (improved sc penetration from increased logp); high-mw polysaccharide → low-mw oligosaccharides (improved penetration + prebiotic activity); protein-bound amino acids → free amino acids and peptides (conditioning + receptor activity).
Typically Found In: Botanical skin care,enhanced delivery
TECHNICAL DETAILS
Primary Category: Active ingredient – antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–5%
SOURCING & ETHICS
Vegan Status: Conditional - supplier confirmation required
Halal Status: Conditional - basis not stated in source record; supplier origin confirmation required to determine what evidence applies
Source Notes: Plant-derived extract or synthetic. [audit 2026-07-29 rev2: status downgraded on audit. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Hydrolysis conditions determine the active profile — mild acid (ph 3-4) releases o-glycosides; enzymatic (specific glycosidase) provides controlled aglycone release; protease digestion generates specific peptide fragment distributions.
Last Verified: 2026-03-22
Primary Sources: Cosing database,hydrolyzed agrimonia pilosa leaf ex hydrolysate enhanced bioavailability review