Common Name(s): Human platelet extract,human platelet extract,human platelet conditioned media,growth factor regenerative active
CAS Number: N/a
DESCRIPTION
What It Does: Delivers the complete cellular signalling cocktail from platelet cells — growth factors, cytokines, exosomes, and matrix proteins activating skin cell renewal and collagen synthesis through simultaneous multi-receptor pathway engagement.
Why It's Used: Conditioned media provides the complete paracrine signalling environment — the synergistic combination of 50-100+ bioactive molecules activating concurrent receptor pathways provides anti-aging responses beyond any single growth factor.
How It Works: Conditioned media: egf → egfr/erk → keratinocyte renewal; fgf-2 → fgfr/pi3k → collagen synthesis; tgf-β → smad2/3 → elastin; vegf → vascularity; secreted exosomes → mirna cargo → gene expression changes in recipient skin cells.
Typically Found In: Premium anti-aging,regenerative skin care,stem cell technology
TECHNICAL DETAILS
Primary Category: Active ingredient – antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–5%
SOURCING & ETHICS
Vegan Status: No - animal-derived
Halal Status: No - blood-derived; prohibited by explicit text (qur'an 5:3)
Source Notes: Plant-derived extract or synthetic. [audit 2026-07-29 rev2: name declares blood or a blood fraction. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Human-derived ingredient regulatory note: human-origin conditioned media and exosomes may require novel cosmetic ingredient notification in some markets (eu art 13 sccs safety assessment); donor testing for infectious agents (hiv, hepatitis) and gmp manufacturing standards are required.
Last Verified: 2026-03-22
Primary Sources: Cosing database,human platelet cm anti-aging review