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HEXAMIDINE

Description

Hexamidine is a potent antimicrobial agent widely used in skincare and pharmaceutical formulations. This synthetic compound belongs to the class of aromatic diamidines and is known for its broad-spectrum activity against bacteria, fungi, and certain parasites. Hexamidine diisethionate, its most common salt form, is particularly effective in combating gram-positive bacteria and Candida albicans.

In skincare, hexamidine is primarily employed for its preservative properties, helping to extend the shelf life of products by preventing microbial growth. Its efficacy at low concentrations makes it an attractive option for formulators seeking to minimize potential irritation while maintaining product integrity. Hexamidine also exhibits mild anti-inflammatory effects, which can be beneficial in treating various skin conditions.

Typical concentration ranges for hexamidine in cosmetic products are between 0.05% to 0.15%. At these levels, it generally demonstrates good skin tolerance, although some individuals may experience sensitivity. Hexamidine is often incorporated into facial moisturizers, eye creams, and acne treatments due to its ability to control microbial populations on the skin surface without excessive drying. Its stability across a wide pH range further enhances its versatility in different formulation types.