Common Name(s): Glucosamine thioctate,glucosamine thioctate,amino acid or sugar derivative,bioactive skin active

CAS Number: N/a

DESCRIPTION

What It Does: Provides receptor-mediated signalling, enzyme cofactor activity, or metabolic support for skin renewal and conditioning.

Why It's Used: Defined molecular structure enables quantifiable pharmacological activity — mechanism-based cosmetic claims from specific receptor or enzyme interactions.

How It Works: Amino acid/sugar derivative interaction with skin: receptor binding → gene expression change; enzyme cofactor → metabolic pathway support; osmolyte → cellular stress protection.

Typically Found In: Targeted skin care

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Typical Concentration Range: 0.01%–2%

SOURCING & ETHICS

Vegan Status: Conditional - crustacean or fungal route; fungal chitosan is vegan

Halal Status: Conditional - crustacean or fungal route; feedstock declaration required

Source Notes: Plant-derived extract or synthetic. [audit 2026-07-29 rev2: chitin family; a fungal route exists that is both halal-simpler and vegan, so origin must be declared. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Verify stability at target formulation ph — amino acid derivatives and sugar conjugates have ph-dependent hydrolysis profiles requiring formulation optimisation.

Last Verified: 2026-03-22

Primary Sources: Cosing database,glucosamine thioctate bioactive amino acid sugar derivative review