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Common Name(s): Ginsenosides,ginsenosides,panax ginseng triterpenoid saponins,adaptogenic anti-aging actives

CAS Number: N/a

DESCRIPTION

What It Does: Provides anti-aging collagen synthesis stimulation from ginsenoside erβ partial agonism, anti-inflammatory nf-kb modulation, and adaptogenic support for skin resilience — the full spectrum of ginseng bioactivity from the standardised saponin fraction.

Why It's Used: Ginsenosides provide the most comprehensive triterpenoid anti-aging profile available — the 35+ distinct saponin species targeting multiple receptors (erβ, glucocorticoid, μ-opioid) simultaneously providing adaptogenic multi-pathway anti-aging.

How It Works: Major ginsenosides: rb1 → erβ activation → col1a1 upregulation; rg3 → nf-kb ikk-β inhibition → anti-inflammatory; rh2 → caspase-3 inhibition → anti-apoptotic; rg1 → nitric oxide synthesis → vasodilation → improved microcirculation. the 20s-protopanaxadiol (ppd) and 20s-protopanaxatriol (ppt) aglycones provide additional receptor activity after gut/skin enzyme hydrolysis.

Typically Found In: Anti-aging,k-beauty premium,adaptogenic

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.01%–2%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Ginsenoside standardisation: total ginsenoside content by hplc is the quality standard — minimum 4% ginsenosides in dried root; 20% in standardised extract. rg1/rb1 ratio indicates red vs white ginseng processing (red ginseng steaming converts rb1 → rg3 providing stronger anti-inflammatory profile).

Last Verified: 2026-03-22

Primary Sources: Cosing database,ginsenosides panax ginseng triterpenoid anti-aging review