Common Name(s): Distearoyl glycerophosphocholine,distearoyl glycerophosphocholine,phospholipid liposome active,biomimetic membrane emollient
CAS Number: N/a
DESCRIPTION
What It Does: Provides sc barrier-identical lipid emolliency from the phospholipid's cell membrane-mimetic architecture, forms liposomal vesicles for encapsulated active delivery, and conditions skin through the phosphocholine head group's sc protein-compatible chemistry.
Why It's Used: Phospholipids provide the most sc-biomimetic emolliency available — the same diacyl-phosphocholine architecture as skin cell membranes providing perfect chemical complementarity for barrier integration.
How It Works: Diacyl phospholipid geometry (cylinder packing parameter ~1) drives lamellar bilayer formation — the same phase as sc lamellar lipid. at concentrations above critical liposome concentration, spontaneous vesicle formation provides encapsulation capacity for hydrophilic and amphiphilic actives with sc-penetrating lamellar vesicle structure.
Typically Found In: Barrier repair,liposome delivery,skin care
TECHNICAL DETAILS
Primary Category: Functional ingredient – emollient
Secondary Functions: Barrier sealing,softening
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–10%
SOURCING & ETHICS
Vegan Status: Conditional - supplier confirmation required
Halal Status: Unverified - supplier confirmation required
Source Notes: Plant-derived, synthetic or animal-derived. verify source. [audit 2026-07-29 rev2: the record's own source_notes does not assert a non-animal origin, or instructs the reader to verify with the supplier; "yes" asserts knowledge the record does not hold. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 1/5 – low; formulation-dependent
Sensitivity Concerns: Non-irritating.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Humectants,ceramides,actives as carrier
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Phospholipid chain length determines liposome stability and fusogenicity: dppc (c16) tm 41°c — gel phase at skin temperature (rigid, low penetration); dopc (c18:1) tm -20°c — fluid phase at all temperatures (fusogenic, good sc integration). formulation phase transition engineering optimises delivery.
Last Verified: 2026-03-22
Primary Sources: Cosing database,distearoyl glycerophosphocholine phospholipid biomimetic liposome emollient review