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DICHLOROPHENYL IMIDAZOLDIOXOLAN

Description

DICHLOROPHENYL IMIDAZOLDIOXOLAN, also known by its trade name Climbazole, is a potent antifungal agent widely used in skincare and personal care products. This synthetic compound belongs to the imidazole class of antifungals and is particularly effective against various species of fungi, including Malassezia, which is associated with dandruff and seborrheic dermatitis.

The molecule's structure consists of a dichlorophenyl group attached to an imidazoldioxolan ring, contributing to its fungistatic and fungicidal properties. Climbazole works by inhibiting ergosterol biosynthesis, a crucial component of fungal cell membranes, thereby disrupting membrane integrity and fungal growth.

In skincare formulations, Climbazole is typically used at concentrations between 0.5% and 2%, depending on the specific application and regulatory guidelines. It is often incorporated into shampoos, conditioners, and scalp treatments to combat dandruff and other fungal skin conditions. Additionally, it can be found in face creams and body lotions targeting fungal acne or other yeast-related skin issues.

Climbazole demonstrates good stability in various formulations and is compatible with many other cosmetic ingredients. Its efficacy, coupled with a relatively low incidence of skin irritation, makes it a valuable component in antifungal skincare products.