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DIBROMOHEXAMIDINE ISETHIONATE

Description

Dibromohexamidine isethionate is a potent antimicrobial agent widely used in skincare and pharmaceutical formulations. This synthetic compound belongs to the class of aromatic diamidines and is known for its broad-spectrum activity against bacteria, fungi, and certain parasites. Its chemical structure consists of two brominated phenyl rings connected by a hexamethylene chain, with isethionate serving as the counter-ion.

In skincare products, dibromohexamidine isethionate primarily functions as a preservative, extending shelf life and preventing microbial contamination. Its efficacy is particularly notable against gram-positive bacteria and various fungal species. The ingredient is typically incorporated at low concentrations, ranging from 0.1% to 0.2%, due to its high potency.

While effective, dibromohexamidine isethionate may cause skin sensitization in some individuals, necessitating careful formulation and patch testing. It is often used in combination with other preservatives to enhance overall product protection. The compound's stability across a wide pH range makes it versatile for various skincare applications, including creams, lotions, and aqueous-based formulations. Regulatory bodies such as the FDA and EMA have approved its use within specified limits, acknowledging its importance in maintaining product safety and integrity.