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DEQUALINIUM CHLORIDE

Description

Dequalinium chloride is a potent antimicrobial agent widely used in skincare and pharmaceutical formulations. This quaternary ammonium compound exhibits broad-spectrum activity against gram-positive and gram-negative bacteria, fungi, and certain viruses. Its efficacy in combating various skin pathogens makes it a valuable ingredient in products designed to treat or prevent skin infections.

In skincare, dequalinium chloride is often incorporated into cleansers, toners, and topical treatments targeting acne, folliculitis, and other bacterial skin conditions. Its mechanism of action involves disrupting microbial cell membranes, leading to cellular death. This ingredient demonstrates particular effectiveness against Propionibacterium acnes, a key contributor to acne development.

Dequalinium chloride typically appears in concentrations ranging from 0.1% to 0.5% in over-the-counter skincare products. Higher concentrations may be found in prescription formulations. While generally well-tolerated, some individuals may experience mild irritation or sensitization. As with many antimicrobial agents, prolonged use could potentially lead to bacterial resistance, necessitating judicious application in skincare regimens.

When formulating with dequalinium chloride, consideration must be given to pH stability and potential interactions with other active ingredients to ensure optimal efficacy and product safety.