Common Name(s): Cytochrome c,cytochrome c,mitochondrial electron transport protein,anti-apoptotic anti-aging active
CAS Number: N/a
DESCRIPTION
What It Does: Scavenges superoxide radicals through the fe²⁺/fe³⁺ redox cycle of the heme iron centre, provides anti-apoptotic signalling preventing premature cell death in uv-stressed skin, and delivers the electron transport protein's unique mitochondria-protective activity.
Why It's Used: Cytochrome c is uniquely positioned at the interface of energy production and apoptosis — when mitochondria are healthy, cyt-c stays in the inner membrane space providing electron transport; when released, it triggers apoptosis. topical supplementation supports the healthy mitochondrial pool.
How It Works: Cytochrome c's fe²⁺ heme reduces o₂•⁻ → o₂ + fe³⁺ → h₂o₂ (superoxide scavenging). in intact mitochondria, cyt-c transfers electrons from complex iii to complex iv; release to cytoplasm triggers caspase-9/3 apoptosis. topical cyt-c may stabilise mitochondrial membrane potential in uv-stressed skin, reducing premature apoptosis.
Typically Found In: Anti-aging,uv repair,mitochondrial support
TECHNICAL DETAILS
Primary Category: Active ingredient – antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.001%–0.1%
SOURCING & ETHICS
Vegan Status: Conditional - supplier confirmation required
Halal Status: Conditional - basis not stated in source record; supplier origin confirmation required to determine what evidence applies
Source Notes: Plant-derived extract or synthetic. [audit 2026-07-29 rev2: status downgraded on audit. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Cytochrome c molecular weight (12 kda) at the upper limit of sc penetration — encapsulation or peptide-mediated targeting may be required for meaningful dermal delivery in anti-aging applications.
Last Verified: 2026-03-22
Primary Sources: Cosing database,cytochrome c mitochondrial anti-aging anti-apoptotic review