Common Name(s): Colloidal gold,noble metal nanoparticle,anti-inflammatory antioxidant

CAS Number: N/a

DESCRIPTION

What It Does: Provides anti-inflammatory activity through nf-kb inhibition from gold nanoparticle-cell membrane interaction, scavenges reactive oxygen species through the nanoparticle surface electron transfer, and provides the premium luxury gold narrative in prestige formulations.

Why It's Used: Gold nanoparticles provide unique photocatalytic antioxidant activity — the surface plasmon resonance absorbs photon energy and transfers it to electron transfer reactions that quench ros, a mechanism unavailable from molecular antioxidants.

How It Works: Au nanoparticles (10–20 nm) exhibit surface plasmon resonance (peak absorbance ~520 nm for 20 nm particles) — photon energy absorbed by the gold surface creates energetic electrons that reduce superoxide and peroxyl radicals. nf-kb inhibition occurs through gold nanoparticle-induced downregulation of ikb kinase.

Typically Found In: Luxury anti-aging,premium skin care

TECHNICAL DETAILS

Primary Category: Active ingredient – antioxidant

Secondary Functions: Free radical scavenging,anti-aging

Application Areas:

Typical Concentration Range: 0.001%–0.1%

SOURCING & ETHICS

Vegan Status: Yes

Halal Status: Yes

Source Notes: Plant-derived extract or synthetic.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Non-irritating; well-tolerated.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Colloidal gold stability in cosmetics requires careful formulation — electrolyte concentration above the critical coagulation concentration (ccc) causes nanoparticle aggregation and colour shift. stabilising with citrate or pvp and maintaining ionic strength below ccc is essential for product stability.

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Primary Sources: Cosing database,colloidal gold nanoparticle anti-inflammatory review