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Common Name(s): Modified chitosan,cationic biopolymer conjugate,antimicrobial conditioning

CAS Number: N/a

DESCRIPTION

What It Does: Provides substantive cationic conditioning deposition on skin and hair through chitosan's electrostatic charge, antimicrobial activity from the lipid modification's membrane disruption, and enhanced skin compatibility from amino acid or succinamide modification.

Why It's Used: Chitosan modification expands the biopolymer's functionality beyond native conditioning โ€” fatty acid conjugation provides antimicrobial membrane-disrupting activity; amino acid conjugation provides skin-complementary chemistry for sensitive skin applications.

How It Works: Protonated chitosan amine groups (pka ~6.5) electrostatically bind negative skin/hair surfaces. fatty acid chains (lauric acid c12) provide optimal antimicrobial membrane activity through logp ~4 partitioning into bacterial membranes. the combined substantive deposition + antimicrobial activity enables prolonged anti-acne or anti-dandruff effects.

Typically Found In: Anti-acne,hair conditioning,antimicrobial skin care

TECHNICAL DETAILS

Primary Category: Active ingredient โ€“ skin microbiome support

Secondary Functions: Microbiome balance,prebiotic effect

Application Areas:

Facial Skincare

Body Care

Hair Care

Beard Care

Color Cosmetics (Makeup)

Dietary/Oral Supplements

Typical Concentration Range: 0.1%โ€“3%

SOURCING & ETHICS

Vegan Status: Conditional - crustacean or fungal route; fungal chitosan is vegan

Halal Status: Conditional - crustacean or fungal route; feedstock declaration required

Source Notes: Fermentation-derived or plant-extracted. [audit 2026-07-29 rev2: chitin family; a fungal route exists that is both halal-simpler and vegan, so origin must be declared. determination requires shariah-panel sign-off.]

SKIN COMPATIBILITY

Irritancy Rating: 1/5 โ€“ very low

Comedogenicity Rating: 0/5 โ€“ non-comedogenic

Sensitivity Concerns: Non-irritating; beneficial for sensitive skin.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,niacinamide,soothing actives

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Chitosan source matters for vegan formulations: traditional chitosan is from crustacean shells (shrimp, crab); fungal chitosan (from aspergillus or rhizopus cell walls) provides a vegan alternative with identical chemistry for sensitive consumers.

Last Verified: 2026-03-12

Primary Sources: Cosing database,chitosan lauroyl glycinate modified chitosan review