Back to Ingredient Dictionary

CETYLPYRIDINIUM CHLORIDE

Description

Cetylpyridinium chloride (CPC) is a quaternary ammonium compound widely used in oral care products and topical antiseptics for its potent antimicrobial properties. This cationic surfactant effectively disrupts bacterial cell membranes, leading to cell death and prevention of microbial growth. In skincare formulations, CPC serves as a preservative and active ingredient, particularly in products targeting acne-prone skin.

CPC exhibits broad-spectrum activity against gram-positive and gram-negative bacteria, fungi, and some viruses. Its efficacy in reducing plaque and gingivitis has led to its inclusion in mouthwashes and toothpastes. In dermatological applications, CPC's antimicrobial action helps combat acne-causing bacteria and maintain product integrity.

Typical concentrations of CPC in skincare products range from 0.1% to 0.5%, depending on the formulation and intended use. While generally well-tolerated, higher concentrations may cause irritation in sensitive individuals. CPC is water-soluble and stable in most formulations, making it a versatile ingredient for various product types. However, its cationic nature can interact with anionic ingredients, necessitating careful formulation considerations. Regulatory bodies, including the FDA, have established safe usage limits for CPC in different product categories.