Common Name(s): Carnitine isomerized linoleate,carnitine isomerized linoleate,carnitine cla ester,beta-oxidation fatty acid active
CAS Number: N/a
DESCRIPTION
What It Does: Provides carnitine-mediated mitochondrial cla delivery for energy metabolism enhancement and cla's documented anti-inflammatory and adipogenic regulatory activity for skin metabolism support.
Why It's Used: Carnitine isomerized linoleate is selected for its dual carnitine transporter and cla bioactive mechanism โ carnitine's acylcarnitine shuttle delivers the isomerized linoleic acid to the mitochondrial beta-oxidation pathway, combining fatty acid energy delivery with cla's anti-inflammatory modulation of ceramide and skin lipid metabolism.
How It Works: Carnitine-cla ester: cpt1 carnitine acyltransferase โ mitochondrial import โ cla beta-oxidation โ energy + propionyl-coa; cla isomer โ ppar-alpha activation โ lipid metabolism + anti-inflammatory signalling.
Typically Found In: Anti-inflammatory,skin metabolism,energy support
TECHNICAL DETAILS
Primary Category: Active ingredient โ antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ3%
SOURCING & ETHICS
Vegan Status: Conditional - feedstock declaration required
Halal Status: Unverified - feedstock declaration required (plant, animal and petrochemical routes all exist)
Source Notes: Plant-derived extract or synthetic. [audit 2026-07-29 rev2: origin-dependent: the same inci exists in plant, animal and petrochemical versions and the name does not discriminate. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
The carnitine moiety provides water solubility for the lipophilic cla โ carnitine esterification is the bioavailability-enhancing strategy for aqueous delivery of conjugated fatty acids.
Last Verified: 2026-03-22
Primary Sources: Cosing database,carnitine isomerized linoleate cla ester beta-oxidation review