Common Name(s): Pot marigold extract,calendula extract
CAS Number: 84776-23-8
DESCRIPTION
What It Does: Heals wounds, reduces inflammation, and soothes irritated skin through faradiol triterpenoid and flavonoid activity.
Why It's Used: Clinically proven traditional wound healing botanical with anti-inflammatory activity comparable to prescription diclofenac in some studies for skin wounds.
How It Works: Faradiol esters inhibit cox-1/cox-2 providing anti-inflammatory activity. polysaccharides promote fibroblast and keratinocyte proliferation. isorhamnetin and narcissin flavonoids provide antioxidant protection. oleanolic acid provides antimicrobial activity.
Typically Found In: Wound healing products,baby products,sensitive skin,post-procedure care
TECHNICAL DETAILS
Primary Category: Active ingredient โ soothing / anti-inflammatory
Secondary Functions: Faradiol triterpenoid anti-inflammatory,wound healing
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%โ5%
SOURCING & ETHICS
Vegan Status: Yes โ calendula officinalis flower-derived
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; ideal for reactive and sensitive skin.
Safe for Sensitive Skin: Yes โ particularly recommended for sensitive skin
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Ceramides,panthenol,allantoin,hyaluronic acid,centella asiatica
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Faradiol monoester and diester triterpenoids are among the most potent naturally occurring cox inhibitors โ ic50 values comparable to indomethacin (a prescription nsaid) for cox-2 inhibition. this explains calendula's clinically observed anti-inflammatory potency exceeding expectations for a cosmetic ingredient.
Last Verified: 2026-03-12
Primary Sources: Cosing database,preethi & kuttan calendula anti-inflammatory study,cir safety assessment