Common Name(s): Calcium hydroxyapatite,calcium hydroxyapatite,hydroxyapatite mineral,biomimetic enamel bone remineralising active

CAS Number: N/a

DESCRIPTION

What It Does: Remineralises tooth enamel through epitaxial crystal growth on demineralised enamel — filling subsurface lesions with structurally identical biomimetic apatite without requiring fluoride.

Why It's Used: Hydroxyapatite provides the most biomimetic enamel remineralisation — identical crystal structure to native enamel enabling seamless integration into the existing enamel lattice.

How It Works: Ha nanocrystals (20-100 nm) adsorb onto demineralised enamel through ca²⁺ electrostatic attraction. epitaxial growth: ha crystals align with existing enamel crystal c-axis orientation filling subsurface lesions. the [ca₁₀(po₄)₆(oh)₂] stoichiometry exactly matches enamel apatite providing identical mechanical properties.

Typically Found In: Oral care,enamel repair,mineral skin care

TECHNICAL DETAILS

Primary Category: Functional ingredient – mineral

Secondary Functions: Mineral support,skin conditioning

Application Areas:

Typical Concentration Range: 0.5%–15%

SOURCING & ETHICS

Vegan Status: Yes – mineral

Halal Status: Yes

Source Notes: Mineral-derived or synthetically produced.

SKIN COMPATIBILITY

Irritancy Rating: 1/5 – very low

Comedogenicity Rating: 0/5 – non-comedogenic

Sensitivity Concerns: Generally non-irritating at cosmetic use levels.

Safe for Sensitive Skin: Yes

SAFETY & COMPATIBILITY

Safety Profile: Excellent safety profile. ewg score: 1.

Works Well With: Ceramides,humectants,skin actives

Avoid Combining With: No significant incompatibilities

SCIENTIFIC NOTE

Calcium hydroxyapatite in skin care: the mineral provides calcium ion conditioning and mild astringency; at nano-scale, surface interaction with skin proteins may provide mild anti-wrinkle mechanical effect.

Last Verified: 2026-03-22

Primary Sources: Cosing database,calcium hydroxyapatite hydroxyapatite remineralisation oral care review