Common Name(s): Bovine dermal fibroblast conditioned media,bovine dermal fibroblast conditioned media,plant cell biotechnology,in-vitro cultured phytochemical active
CAS Number: N/a
DESCRIPTION
What It Does: Provides standardised, quantifiable concentrations of the plant's active polyphenols and secondary metabolites from controlled in-vitro production — delivering consistent bioactivity unavailable from field-harvested plant material with natural compositional variation.
Why It's Used: In-vitro plant cell technology provides pharmaceutical-grade standardisation for cosmetic actives — the same composition batch-to-batch enables reliable clinical claim substantiation. methyl jasmonate or uv elicitation elevates secondary metabolite production 2-10x above in-planta levels.
How It Works: Callus or suspension culture cells grown in defined bioreactor medium under controlled elicitation stress (uv, methyl jasmonate, yeast elicitor) → secondary metabolite pathway activation → 2-10x active concentration above in-planta levels. downstream extraction provides standardised active concentrate with coa for key marker compounds.
Typically Found In: Premium active serums,sustainable beauty,rare plant actives
TECHNICAL DETAILS
Primary Category: Active ingredient – antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.1%–5%
SOURCING & ETHICS
Vegan Status: No - animal-derived
Halal Status: Conditional - donor species and culture medium composition required (bovine serum is a second origin question)
Source Notes: Plant-derived extract or synthetic. [audit 2026-07-29 rev2: animal donor cell culture; donor species and medium composition undocumented. determination requires shariah-panel sign-off.]
SKIN COMPATIBILITY
Irritancy Rating: 1/5 – very low
Comedogenicity Rating: 0/5 – non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
In-vitro cell culture enables cosmetic use of actives from cites-protected, endangered, or slowly growing plants — providing authentic phytochemistry from sustainable biotechnology production without field harvesting pressure on wild populations.
Last Verified: 2026-03-22
Primary Sources: Cosing database,bovine dermal fibroblast conditione plant cell culture biotechnology review