Back to Ingredient Dictionary

AMINOPHYLLINE

Description

Aminophylline is a xanthine derivative compound that has gained attention in the skincare industry for its potential benefits in topical applications. This ingredient is primarily known for its bronchodilator properties in medical settings but has been repurposed for cosmetic use. In skincare formulations, aminophylline is believed to promote lipolysis, the breakdown of fat cells, which has led to its incorporation in various anti-cellulite and body contouring products.

The mechanism of action for aminophylline in skincare involves inhibiting phosphodiesterase, an enzyme that breaks down cyclic AMP. By increasing cyclic AMP levels, aminophylline may stimulate lipolysis in adipocytes, potentially reducing the appearance of cellulite and improving skin texture. Additionally, it is thought to enhance microcirculation in the skin, which may contribute to a more even skin tone and improved overall appearance.

Typical concentrations of aminophylline in skincare products range from 0.5% to 2%. While some studies suggest its efficacy in reducing the appearance of cellulite, more comprehensive research is needed to fully establish its long-term benefits and optimal usage in topical applications. As with any active ingredient, patch testing is recommended to assess individual skin tolerance.