Back to Ingredient Dictionary

ALLOFERON-1

Description

Alloferon-1 is a novel peptide originally isolated from the immune system of insects, specifically the blow fly Calliphora vicina. This unique compound has garnered significant interest in the dermatological and cosmeceutical fields due to its potential immunomodulatory and anti-viral properties. Composed of just 13 amino acids, Alloferon-1 has been shown to stimulate natural killer (NK) cell activity and enhance the production of interferon, key components of the innate immune response.

In skincare formulations, Alloferin-1 is primarily utilized for its potential to boost the skin's natural defense mechanisms against environmental stressors and pathogens. Research suggests it may help improve the skin's resilience and overall health by modulating immune responses at the cellular level. Some studies indicate possible benefits in addressing viral skin conditions, such as herpes simplex outbreaks.

Alloferon-1 is typically incorporated into serums, creams, and other topical preparations at low concentrations. Its small molecular size may contribute to effective skin penetration. While promising, more extensive clinical studies are needed to fully elucidate its long-term efficacy and safety profile in various skin types and conditions.