Common Name(s): Adenosine cyclic phosphate,adenosine monophosphate/cyclic amp,purine nucleotide,p2y signalling anti-aging
CAS Number: N/a
DESCRIPTION
What It Does: Provides rapid atp precursor for cellular energy replenishment (amp) or direct camp second messenger activity (cyclic amp) activating pka for anti-aging lipolysis and collagen synthesis signalling.
Why It's Used: Adenosine nucleotides provide the purine backbone for the skin's energy and signalling systems โ the distinct phosphorylation state determines whether the molecule acts as an energy substrate (amp โ atp) or as a hormone-mimetic second messenger (camp โ pka).
How It Works: Amp โ adenylate kinase (2 amp โ adp + atp) โ rapid atp resynthesis for energy-depleted skin cells. cyclic amp โ pka-cฮฑ/ฮฒ subunit dissociation โ phosphorylation of creb, hsl (lipolysis), and collagen promoter binding proteins โ anti-aging and anti-cellulite gene expression. camp is the shared second messenger for beta-adrenergic, prostaglandin e2, and glucagon receptor pathways.
Typically Found In: Anti-aging,cellular energy,anti-cellulite
TECHNICAL DETAILS
Primary Category: Active ingredient โ antioxidant
Secondary Functions: Free radical scavenging,anti-aging
Application Areas:
Facial Skincare
Body Care
Hair Care
Beard Care
Color Cosmetics (Makeup)
Dietary/Oral Supplements
Typical Concentration Range: 0.001%โ0.5%
SOURCING & ETHICS
Vegan Status: Yes
Halal Status: Yes
Source Notes: Plant-derived extract or synthetic.
SKIN COMPATIBILITY
Irritancy Rating: 1/5 โ very low
Comedogenicity Rating: 0/5 โ non-comedogenic
Sensitivity Concerns: Non-irritating; well-tolerated.
Safe for Sensitive Skin: Yes
SAFETY & COMPATIBILITY
Safety Profile: Excellent safety profile. ewg score: 1.
Works Well With: Vitamin c,vitamin e,ferulic acid,spf,other antioxidants
Avoid Combining With: No significant incompatibilities
SCIENTIFIC NOTE
Camp membrane permeability: cyclic amp is membrane-impermeant โ topical application provides extracellular camp that is internalized through slc22 organic anion transporters in keratinocytes and fibroblasts for intracellular pka activation.
Last Verified: Cosing database,adenosine cyclic phosphate adenosine nucleotide purine anti-aging review
Primary Sources: 2026-03-22