
ACETYL HEXAPEPTIDE-8 AMIDE
Description
Acetyl Hexapeptide-8 Amide, also known as Argireline, is a synthetic peptide compound that has gained significant attention in the skincare industry for its potential anti-aging properties. This ingredient is a fragment of SNAP-25, a protein involved in the formation of wrinkles. By mimicking this protein, Acetyl Hexapeptide-8 Amide is believed to inhibit the release of neurotransmitters responsible for muscle contractions, potentially reducing the appearance of fine lines and wrinkles.
The compound works by targeting the neuromuscular junction, temporarily limiting muscle movement in a manner similar to botulinum toxin, but without the need for injections. Studies have shown that topical application of Acetyl Hexapeptide-8 Amide can lead to a reduction in wrinkle depth, particularly around the eyes and forehead. Its molecular weight allows for penetration through the skin barrier, enhancing its efficacy when used in cosmetic formulations.
Typically incorporated at concentrations between 2-10%, this ingredient is compatible with various skincare formulations, including serums, creams, and lotions. While generally well-tolerated, long-term safety data is still limited, and results may vary among individuals.