
7-DEHYDROCHOLESTEROL
Description
7-Dehydrocholesterol (7-DHC) is a crucial precursor molecule in vitamin D synthesis and plays a significant role in skin health. This naturally occurring sterol is found in the epidermis, where it acts as a substrate for the production of vitamin D3 when exposed to ultraviolet B (UVB) radiation from sunlight. The conversion of 7-DHC to vitamin D3 is a critical step in maintaining adequate vitamin D levels in the body.
In skincare formulations, 7-DHC is utilized for its potential to enhance the skin's natural vitamin D production and improve overall skin barrier function. It may help strengthen the skin's defense against environmental stressors and support cellular repair processes. Some studies suggest that topical application of 7-DHC can increase local vitamin D synthesis, potentially benefiting conditions such as psoriasis and eczema.
However, it's important to note that excessive accumulation of 7-DHC can lead to oxidative stress and may contribute to certain skin disorders. Therefore, its use in skincare products must be carefully balanced and formulated. When incorporated into skincare regimens, 7-DHC is typically used in low concentrations and often combined with antioxidants to maximize its benefits while minimizing potential risks.