Back to Ingredient Dictionary

HUMAN KERATINOCYTES

Description

Human keratinocytes are the predominant cell type in the epidermis, comprising approximately 90% of the cells in this outer layer of skin. These specialized cells play a crucial role in maintaining skin barrier function and protecting the body from external threats. Keratinocytes produce and store keratin, a fibrous protein that provides structural integrity and waterproofing properties to the skin.

In skincare formulations, human keratinocytes are typically utilized in the form of cultured cell extracts or conditioned media. These derivatives contain a complex mixture of growth factors, cytokines, and peptides that can support skin regeneration and repair processes. Key benefits of keratinocyte-derived ingredients include promoting wound healing, stimulating collagen production, and enhancing epidermal turnover.

When incorporated into topical products, human keratinocyte extracts may help improve skin hydration, reduce the appearance of fine lines, and support overall skin health. However, it's important to note that the efficacy of these ingredients can vary depending on the extraction method, concentration, and formulation stability. Proper preservation and delivery systems are essential to maintain the bioactivity of keratinocyte-derived components in skincare products.