Back to Ingredient Dictionary

HEXETIDINE

Description

Hexetidine is a synthetic antimicrobial agent widely used in oral care and skincare products. This broad-spectrum compound exhibits potent activity against both gram-positive and gram-negative bacteria, as well as certain fungi. Its chemical structure, featuring a hexahydropyrimidine ring, contributes to its efficacy in combating various microorganisms.

In skincare formulations, hexetidine is primarily employed for its antibacterial and antifungal properties. It is particularly effective in treating acne-prone skin by reducing the proliferation of Propionibacterium acnes, a key contributor to acne development. Hexetidine also helps in managing conditions like seborrheic dermatitis and fungal infections of the skin.

The ingredient's mechanism of action involves disrupting the cell membranes of microorganisms, leading to their death. This property makes hexetidine valuable in preserving cosmetic products and extending their shelf life. Typical concentrations in skincare products range from 0.1% to 0.3%, balancing efficacy with skin tolerance.

While generally well-tolerated, some individuals may experience mild irritation or allergic reactions. As with any active ingredient, patch testing is recommended before widespread use, especially for those with sensitive skin.