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DODECYLTRIPHENYLPHOSPHONIUM BROMIDE

Description

Dodecyltriphenylphosphonium bromide is a quaternary phosphonium compound with distinctive properties that make it valuable in skincare formulations. This synthetic ingredient functions primarily as a preservative and antimicrobial agent, helping to extend the shelf life of cosmetic products and protect against bacterial contamination.

The molecule consists of a triphenylphosphonium group attached to a twelve-carbon alkyl chain, with bromide as the counterion. Its amphiphilic structure allows it to interact with both lipids and water, enhancing its efficacy across various product types. Dodecyltriphenylphosphonium bromide exhibits broad-spectrum antimicrobial activity against both gram-positive and gram-negative bacteria, as well as some fungi.

In skincare formulations, it is typically used at low concentrations, ranging from 0.1% to 0.5%, depending on the product type and desired preservation efficacy. Its compatibility with a wide range of cosmetic ingredients makes it versatile for use in creams, lotions, serums, and other topical preparations. While effective as a preservative, it's important to note that some individuals may experience skin sensitization, necessitating patch testing before widespread use in products.